Association of GT microsatellite polymorphism in TLR 2 gene with leprosy

نویسندگان

  • NC Suryadevara
  • NV Sanjeev
  • Vijaya Lakshmi Valluri
  • Suman Jain
  • MPJS Anandraj
چکیده

Background Toll-like receptor 2 (TLR2) is critical in bringing up immune responses to mycobacterial infections. The mutations in TLR2 are known to confer susceptibility for severe infection with mycobacteria. TLR2 may diminish response to mycobacterial proteins and place individuals at risk of developing leprosy. We investigated the association of GT repeat polymorphism in intron2 of TLR2 gene with leprosy in south Indian patients.

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عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2012